The popular Spaniard turned pro in 2003 and spent the final six years of his cycling journey here at Team Sky.
After weighing up his options for 2019 Lopez, 37, decided to bring his time in the peloton to an end and is looking forward to a life after racing.
“I decided to stop at 37 after 16 years racing as a pro,” he told TeamSky.com. “It's a good moment. I had started to look at other options for next year but it's a difficult period, with teams cutting down on riders because there's less riders in every race.
“I had some options to continue on smaller teams in Spain but I worried it would be difficult to drop down. The desire might not have been the same and I preferred to stop and try something different rather than ride on with doubts about my motivation for training and racing.”
Lopez, who joined the team from Movistar in 2013, has enjoyed six strong years here and when asked for his highlight he answers in a flash: “When we won the Tour in 2013. That was a nice moment. It was my first year in the team, everything was new, and I had the chance to ride the Tour in my first year - that was very big for me.
“I’d always been with Spanish teams then I took the big decision to move to Sky and in my first year I went straight to the Tour, where we won with Froomey. It was a special time for me.”